The Blaine Act, a congressional bill sponsored by Wisconsin senator John J. Blaine, is passed by the U.S. Senate and officially repeals the 18th Amendment to the United States Constitution, aka the Volstead Act, aka Prohibition. The repeal is formally adopted as the 21st Amendment to the Constitution on December 5, 1933.

The state radio channel known as Voice of America and controlled by the U.S. State Department, begins broadcasting into the Soviet Union in Russian with the intent of countering Soviet radio programming directed against American leaders and policies. The Soviet Union responds by initiating electronic jamming of VOA broadcasts.

Wallace H. Carothers, an American chemist, inventor and the leader of organic chemistry at DuPont Corporation, receives a patent for a silk substitute fabric called nylon. Carothers was a depressive who for years carried a cyanide capsule on a watch chain in case he wanted to commit suicide, but his genius helped produce other polymers such as neoprene and polyester. He eventually did take cyanide—not in pill form, but dissolved in lemon juice—resulting in his death in late 1937.

In Miami, Florida, Giuseppe Zangara attempts to shoot President-elect Franklin D. Roosevelt, but is restrained by a crowd and, in the course of firing five wild shots, hits five people, including Chicago, Illinois Mayor Anton J. Cermak, who dies of his wounds three weeks later. Zangara is quickly tried and sentenced to eighty years in jail for attempted murder, but is later convicted of murder when Cermak dies. Zangara is sentenced to death and executed in Florida's electric chair.